NFL Week 7 Injury Updates: J.J. McCarthy, Kyler Murray, Brock Purdy Return Status & More (2025)

Get ready for an intense dive into the world of NFL injuries as we head into Week 7 of the 2025 season! Injuries are mounting, and some teams are feeling the heat more than others. The San Francisco 49ers, for instance, have been hit hard, with the loss of their durable linebacker, Fred Warner, for the entire season. It's a tough blow for any team, but the 49ers aren't alone in their injury woes.

Week 6 saw some devastating injuries across the league. The Indianapolis Colts had a rough start even before their game against the Cardinals, with backup QB Anthony Richardson and cornerback Charvarius Ward sustaining injuries during pregame warmups. And that's not all; star players like David Njoku, Trey Hendrickson, and Marvin Harrison Jr. also had to leave their respective games early due to injuries.

But here's where it gets controversial... some key quarterbacks are on the road to recovery, and their potential return could shake up the league. We're talking about J.J. McCarthy, Brock Purdy, and Kyler Murray. These guys are inching closer to returning to the field, and their teams are eagerly awaiting their comeback.

Let's dive into the details and explore the latest injury updates as we head into Week 7.

J.J. McCarthy's Return?

Vikings quarterback J.J. McCarthy is making progress after suffering a high ankle sprain last month. He participated in Wednesday's practice, albeit with some limitations, as the team prepares for their game against the Philadelphia Eagles. While McCarthy admits his ankle isn't 100%, he's confident he's getting there. If he can't play, the Vikings have a backup plan with Carson Wentz ready to step in.

49ers' Purdy and Kittle Back in Action?

Good news for the 49ers! Quarterback Brock Purdy and tight end George Kittle are expected to return to practice this week. Kittle, who's been on injured reserve since Week 2, is eager to get back on the field after missing at least four games. If Purdy isn't ready, Mac Jones will likely take over as QB1 against the Falcons. Jones has also been dealing with injuries this season, so it's a wait-and-see situation for the 49ers.

Cardinals' Murray Limited

Cardinals quarterback Kyler Murray was limited during Wednesday's practice due to a foot injury. Jacoby Brissett, the QB2 for Arizona, is ready to step in if Murray can't play. Brissett started in place of Murray last week against the Colts and put up some impressive numbers. The Cardinals are currently on a four-game losing streak and will face the Packers this week, so Murray's availability is crucial.

Other Injury Updates:

  • Bengals defensive end Trey Hendrickson is questionable for Thursday's game against the Steelers due to a hip injury.
  • Chargers have opened the 21-day practice window for EDGE Khalil Mack, who's been on IR since Week 2.
  • Titans have designated NT T'Vondre Sweat to return to practice, opening his 21-day window to be activated from IR.
  • Cardinals have opened the practice window for first-round rookie DL Walter Nolen III, who's been on the PUP list since training camp began.
  • Cowboys star wide receiver CeeDee Lamb is returning to practice and is trending toward playing this weekend.
  • Commanders have placed wide receiver Noah Brown on IR with a groin injury, but wide receiver Terry McLaurin is expected to practice this week.
  • Jets wide receiver Garrett Wilson is missing practice due to a knee injury, but initial MRI results show he avoided a serious injury.
  • Bengals have placed tight end Mike Gesicki on IR with a pectoral injury, which will impact their tight end group.
  • Lions defensive tackle Alim McNeill is set to return from an ACL injury and make his 2025 season debut in Week 7 against the Buccaneers.
  • Falcons left tackle Jake Matthews is day-to-day with an ankle injury.
  • New York Jets wide receiver Garrett Wilson is expected to miss a couple of weeks after hyperextending his knee.
  • 49ers are hoping to have star tight end George Kittle back at practice this week.
  • Colts backup quarterback Anthony Richardson is likely to miss multiple games after sustaining an orbital fracture during pregame warmups.
  • Buccaneers running back Bucky Irving and wide receiver Chris Godwin are likely out next week due to foot and fibula injuries, respectively.
  • Rams star wide receiver Puka Nacua is expected to miss time with an ankle sprain.
  • Cardinals wide receiver Marvin Harrison Jr. is dealing with a concussion and will need to clear the league's concussion protocol before returning.
  • 49ers wide receiver Jauan Jennings has been playing through some serious injuries, including five broken ribs and ankle sprains.

These injury updates are crucial as we head into Week 7. Who will make a comeback, and who will be sidelined? Stay tuned, and let's discuss in the comments! Are there any players you're particularly concerned about? Share your thoughts, and let's keep the conversation going!

NFL Week 7 Injury Updates: J.J. McCarthy, Kyler Murray, Brock Purdy Return Status & More (2025)

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